Biofilms, which are communities of microorganisms that are attached to a surface, play a critical role in numerous infectious diseases. The U.S. Centers for Disease Control (CDC) and National Institutes of Health (NIH) recently estimated that biofilms are responsible for 65% to 80% of all infections. In 2008, the Cellular and Molecular Immunology B Study Section (CMIB) established a multi-disciplinary translational biofilms research group that consists of microbiologists, immunologists, biochemists, pathologists, computational biologists, infectious diseases experts, as well as pulmonary and otolaryngology specialists. The team meets monthly to discuss scientific and programmatic themes with the goal to submit an NIH program project grant.